How the acetogenins from Paw Paw can help fight cancer
Written by Steven Horne
In spite of decades of research cancer continues to be the number two killer in the United States and other civilized countries. Almost half of U.S. men and women will eventually be diagnosed with a malignant, cancerous growth. About one-third of U.S. men and women will die from cancer.
🔥 Cancer Cells About
Cancer cells are the result of damage (mutations) to DNA in the cell's nucleus that turns a healthy cell into a type of parasite. Cancer cells grow much faster than ordinary cells competing with healthy cells for nutrients. Having lost their normal control systems for growth, cell division and death, these cells multiply out of control. They attract new blood vessels to themselves to feed their runaway appetites for the nutrients needed for their out-of-control growth. Cancers can grow "tentacles" to reach out and invade other areas. Cancers can even clone themselves. When they travel through the blood stream and lymphatic system, they metastasize throughout the body.
What if you could take something that would selectively deprive cancer cells of the energy they need to feed their rapid growth and reproduction, without harming healthy cells?
What if, as positive side effects, this same substance could enhance the effectiveness of standard chemotherapy.
What if it could also help your body deal with parasitic organisms such as intestinal worms, yeast infections, and even head lice?
Years of research by Dr. Jerry McLaughlin, MDhave confirmed that substances which can accomplish these tasks can be found in the leaves, unripe fruits and twigs of the humble paw paw tree, a deciduous tree that grows all over the Eastern United States.
The Paw Paw Anticancer Program
🧠 How Cancer Develops
As was discussed above, cancer cells develop when the DNA of a healthy cell becomes damaged, causing that cell to mutate. Although genetic weaknesses and predispositions may contribute to the occurrence of cancers, environmental influences such as chemicals, radiation, and viruses are involved most of the time. The liver detoxifies and eliminates many chemicals that might cause cancer. Most traditional anticancer herbal formulas actually help by improving liver function. The liver also destroys excess estrogen, which is a signal for cellular growth and increases the development of cancers, especially in women.
It may take years for a primary tumor to grow large enough to be seen or felt as a lump. Cancer may spread through the system of lymph nodes. In very serious cases, cancer cells, traveling through the blood, may metastasize in other tissues such as the brain, lungs, or liver.
Paw paw contains compounds called annonaceous acetogenins. These compounds inhibit the production of ATP inside the cell by blocking complex I in the mitochondria. This triggers apoptosis. In other words, paw paw "convinces" cells to self destruct. These acetogenin compounds are found in plants in the Annonaceae family, which contains about 2,100 species of plants, most of which grow in the tropics. Paw paw is the only deciduous member of this family and has one of the highest amounts of these compounds. The amount of acetogens varies widely from plant to plant and even seasonally, but Dr. Jerry McLaughlin was able to create a standardized extract of these substances which can be used for a wide variety of purposes.
🙋 Are There Any Side Effects?
One of the main problems with traditional cancer therapies such as radiation and chemotherapy is that they damage healthy cells as well as cancer cells. So, the question naturally arises, if acetogenins block ATP production, wouldn't that affect healthy cells, too? Well, it does slow down the function of healthy cells, but since the cancer cells use energy at a rate up to 17 times faster than normal cells, the compounds have the strongest effect against the rapid metabolism of the cancer cells.The abnormal cancer cells are induced to self destruct due to the reduced metabolism, while healthy cells remain undamaged.
Before being released, this paw paw extract was provided to 130 cancer patients for up to one and a half years. Only three of those in the study reported nausea and vomiting and one reported itching. None had any typical chemotherapy problems such as bone marrow suppression, anemia, hair loss, etc. The extract is now available in the product Paw Paw Cell-Reg.
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🌿 Using Paw Paw Extract
The suggested use of Paw Paw Cell Reg is 4 capsules per day until after remission. People using the product are finding it beneficial to combine it with Immune Stimulator and High Potency Protease (both taken between meals).
Protease activates immune activity, including Natural Killer (NK) cells, against cancers. It makes cancer cells and, viruses more discernible to the immune system. Immune Stimulator stimulates the immune system and improves elimination.
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Milk Thistle Combination ![]() |
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Immune Stimulator ![]() |
This program would typically be used as an alternative or supplement to chemotherapy, then continued for a month beyond the time that all tumor markers are down and there is no further evidence of the cancer. Additionally, it can be used at least once a month for the next 2-3 years.
✅ Research on Paw Paw
Dr. Jerry McLaughlin is the world's leading authority on paw paw after spending many years at Purdue University doing research on the plant. Nature's Sunshine has an exclusive right to distribute this patented product. Dr. McLaughlin discovered that paw paw contains a group of plant chemicals called annonaceous acetogenins. There are over 50 of these long chain fatty acids in paw paw.
Research has established that these acetogenins:
- Slow and stop the production of cell energy in cells by blocking the production of ATR
- Prevent the growth of new blood vessels in or near tumors.
- Deplete DNA and RNA building blocks needed for abnormal cell division.
- Kill even those cells that are resistant to chemotherapy drugs.
- Prevent cells from activating ATP-fueled metabolic pumps that may reject chemotherapy drugs.
- Is up to 300 times more potent than Taxol, without inducing weight loss.
A comprehensive review article was published in the January 1999 issue of the Journal of Natural Products, and McLaughlin's group has over 100 papers already published on the paw paw compounds.
🚫 Products to Avoid
While using this program, products that increase cellular vitality, especially those that increase energy metabolism, should be avoided. Antioxidants also decrease the effectiveness of the paw paw extract.
Supplements to be avoided include Co Q10, SOD, Super Antioxidants, Grapine, Alpha Lipoic Acid, Cellular Energy, N-Acetyl Cysteine, Garlic, IGF-1, 7 Keto, Para-Cleanse, TS II and Thyroid Activator.
Because these supplements increase energy production and inhibit cellular damage, they reduce the effectiveness of the paw paw extract. Thyroid Activator, for instance, would stimulate the thyroid gland to secrete hormones that would raise the production of ATP in the cells.
Don't use the new Para-Cleanse with Paw Paw and the Paw Paw Cell-Reg together. This avoids consuming more paw paw extract than is needed.
✨ What to Expect
First, it is unlikely one would overdose on paw paw extract because vomiting occurs before too much can be consumed. If nausea or vomiting do occur, simply lower the dose.
It is typical to see significant reductions in tumor size and in tumor antigen levels within six to eight weeks. Some people report a more rapid, measurable response to the program. For instance, one lady saw an improvement in her CA-125 markers (Cancer Antigen 125 is used to monitor ovarian cancer) after only one week. In a patient with non-Hodgkins lymphoma, who had undergone three rounds of chemotherapy in six and a half years, the white cell count and lymphocytes returned to normal ranges after only 35 days of taking paw paw extract. People who have cancer who take Paw Paw Cell-Reg are also reporting increased energy levels. This is because paw paw's inhibiting effect on the metabolism of cancer cells means that healthy cells no longer have to compete with cancer cells for energy.
This is not a cancer prevention product to be taken by healthy people. In fact, the list of supplements to avoid while using paw paw extract includes products normally used to help prevent the development of cancer. So, save this product for when you really need it.
People are also reporting results with Paw Paw Cell Reg in inhibiting viral conditions such as cold sores and shingles. It appears to inhibit replication of the viruses.
🌼 Paw Paw and shingles
Paw Paw Cell Reg is helpful in fighting chronic viral conditions like Shingles and Herpes because viruses require ATP to reproduce. The acetogenins in Paw Paw inhibit the production of ATP in the mitochondria of cells and helps the immune system fight the infection.
📌 Disclaimer: All content on this website is intended for informational use only and does not constitute medical advice. Always seek the guidance of a licensed healthcare professional regarding any medical condition or treatment.



